Antioxidants fight toxic root of ALS

Reader’s Question: A long-term, and close friend has been diagnosed with ALS. He’s already lost his ability to speak and is having some issues with breathing/swallowing. Is there any hope on the horizon?

Dr. Glenn Rothfeld: You may know ALS (amyotrophic lateral sclerosis) by its more common name, Lou Gehrig’s disease.

This “nickname” came after the disease struck home-run-hitting major-league baseball player Lou Gehrig back in 1939.

In this fast-progressing disease, motor nerves are lost throughout the nervous system.

After his diagnosis, Gehrig deteriorated very rapidly: Less than two years after his initial symptoms of weakness and stumbling appeared, he suffered a helpless, totally-paralyzed death.

The same has happened to nearly all other ALS victims. This terrible disease is terminal… and there is no known cure.

However, there are three antioxidants that I find may be useful in the treatment (and, actually, prevention) of ALS.

First of all, there’s resveratrol. Findings from animal studies suggest that this antioxidant:

• decreases the brain damage associated with ALS symptoms by activating a protein called SIRT1, which is responsible for keeping cells working longer and better
• buffers the damage caused by the neurotransmitter glutamate, which builds up in the brains of ALS patients, resulting in a flood of messages that overwhelms and damages brain cells
• prevents the elevation of calcium in ALS patients whose metabolism of it is aberrant
• prevents and reduces oxidation, high levels of which are associated with ALS.

Secondly, one of the primary antioxidants that keeps the brain healthy is called glutathione. I believe that most cases of ALS are actually a neurotoxic  problem, and glutathione also happens to be an effective chelating agent for the removal of toxic minerals

The best way to increase your brain levels of this “master antioxidant” isn’t actually by supplementing with it directly, but by taking a compound known as N-acetylcysteine, or NAC for short.

Lastly, as I shared with you last year, ALS seems to be amenable to being treated with the simplest antioxidant, hydrogen. In fact, hydrogen is the simplest of ALL molecules – found in all plants, the human body, and even the sun.

Drinking hydrogen water gets the hydrogen into the bloodstream rapidly and efficiently – and hydrogen is so small that it can even cross the blood-brain barrier, but so mild and innocuous that it doesn’t affect the normal function of the cells.

And remarkably, hydrogen can be dissolved into water without changing the water itself, nor its taste, color, or other properties.

At my clinic in the Boston area, we’re currently using a GMO-free supplement product called “H2 Absorb.” You can plop this tablet into a bottle of water, and it will dissolve hydrogen into it while it fizzes.

Keep those great questions coming. Drop me a line at, and I may choose yours to answer next week.

Wishing you the best of health,

Dr. Glenn S. Rothfeld
Nutrition & Healing
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